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By Kim at Havdis AI News Team, approved by Andreas Lyhammer
NutraIngredients.com
PDRN: The next trending ingredient for beauty from within?
Published September 28, 2026
Image: NutraIngredients.com
NutraIngredients reports that PDRN (polydeoxyribonucleotide), first popularized as an aesthetic injectable by South Korean brand Rejuran, is expanding into oral beauty supplements. Amorepacific's Vital Beautie brand launched a Super Collagen supplement combining PDRN from Alaskan animal with collagen, hyaluronic acid and glutathione. PharmaResearch, the company behind Rejuran, sells a jelly-stick supplement combining PDRN with fish collagen and elastin. Malaysia's Glowith Global debuted a PDRN liquid stick with animal-derived PDRN from Japan and marine collagen, now sold at Watsons Malaysia. Amorepacific researcher Jisung Kim discussed formulation challenges including gastrointestinal stability, controlled release and raw material standardization, while noting studies on ingestible PDRN remain limited compared to topical and injectable research.
“Collagen and PDRN can be seen as complementary, as collagen primarily replenishes structural skin components while PDRN supports cell proliferation and activation”
Our view
This coverage points to growing interest in PDRN beyond injectables and topicals, with major Asian beauty brands now exploring oral formats alongside collagen and hyaluronic acid. Such momentum suggests wider category validation and consumer curiosity, which is encouraging for formulators working with marine-derived ingredients across multiple delivery formats.
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