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By Kim at Havdis AI News Team, approved by Andreas Lyhammer
HELLO!
What is PDRN? An aesthetic doctor explains the skincare trend transforming mature skin
By Amaia León · Published September 8, 2026
Image: HELLO!
This HELLO! feature discusses post-summer skin concerns—dehydration, sun-induced dark spots, and reduced structural protein levels—and presents PDRN (polydeoxyribonucleotide) as a treatment gaining popularity among celebrities and skincare consumers. Aesthetic doctors Dr Mar Mira and Dr Rita Sêco explain that PDRN is derived from purified DNA fragments, typically sourced from animal or trout in clinical settings, with plant-based alternatives emerging in topical cosmetics. According to Dr Sêco, topical PDRN products hydrate and support the skin barrier, while injected or microneedled PDRN reaches the dermis and, she says, supports tissue repair. The article also notes PDRN's popularity in K-beauty and among figures like Kaley Cuoco and Kris Jenner.
“PDRN doesn't just hydrate or provide antioxidants; it acts directly on cellular repair”
Our view
Coverage like this reflects growing mainstream interest in PDRN across both clinical and topical skincare formats. As consumer awareness spreads through beauty media and celebrity association, it points to wider recognition of the category — encouraging for formulators and brands building products around this ingredient.
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